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Assay Detail

CHEMBL653246

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitor concentration against Beta-galactosidase from Aspergillus niger
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Aspergillus niger
Confidence 9 — Direct single protein target
Curated By Intermediate

Target

Beta-galactosidase (CHEMBL4753)
Type SINGLE PROTEIN
Organism Aspergillus niger

Publication

Synthesis of [(2S,3S,4R)-3,4-dihydroxypyrrolidin-2-yl]-5-methylfuran-4-carboxylic acid derivatives: new leads as selective beta-galactosidase inhibitors.
Moreno-Vargas AJ, Demange R, Fuentes J, Robina I, Vogel P.
Bioorg Med Chem Lett (2002) 12 : 2335 -2339
PubMed 12161128 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 4.84 5.12

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2114148 1 5.12
CHEMBL2114149 1 4.55
CHEMBL3350284 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2114148 IC50 = 7500.0 nM 5.12
CHEMBL2114149 IC50 = 28000.0 nM 4.55
CHEMBL3350284 IC50 = 370000.0 nM -