Assay Detail
Binding
CHEMBL653277
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Inhibitory activity against Beta-lactamase from DMSO stock was determined
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
A specific mechanism of nonspecific inhibition.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.26 | 5.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1160008 | IODOPHTHALEIN | 2.0 | 1 | 5.52 |
| CHEMBL50 | QUERCETIN | 3.0 | 1 | 5.40 |
| CHEMBL429694 | CONGO RED | -1.0 | 1 | 5.40 |
| CHEMBL1484 | NICARDIPINE | 4.0 | 1 | 4.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1160008 | IODOPHTHALEIN | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL50 | QUERCETIN | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL429694 | CONGO RED | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL1484 | NICARDIPINE | IC50 | = | 20000.0 | nM | 4.70 |