Assay Detail
Functional
CHEMBL653334
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Tested for in vitro cell growth inhibition of CALU-1 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Calu-1 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis, antiproliferative, and antiviral activity of 4-amino-1-(beta-D-ribofuranosyl)pyrrolo[2,3-d]pyridazin-7(6H)-one and related derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.90 | 7.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL609505 | — | — | 1 | 7.16 |
| CHEMBL2093055 | — | — | 1 | 6.64 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL609505 | — | IC50 | = | 70.0 | nM | 7.16 |
| CHEMBL2093055 | — | IC50 | = | 230.0 | nM | 6.64 |