Assay Detail
Binding
CHEMBL653508
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Inhibitory activity against recombinant human Beta-secretase 1
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Green tea catechins as a BACE1 (beta-secretase) inhibitor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.24 | 6.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL126079 | — | — | 1 | 6.77 |
| CHEMBL338988 | — | — | 1 | 6.68 |
| CHEMBL126142 | — | — | 1 | 5.28 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL126079 | — | Ki | = | 170.0 | nM | 6.77 |
| CHEMBL338988 | — | Ki | = | 210.0 | nM | 6.68 |
| CHEMBL126142 | — | Ki | = | 5300.0 | nM | 5.28 |