Assay Detail
Functional
CHEMBL654533
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for stimulation of mitogenesis in CHO.hD3 cells in a dose dependent manner
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cricetulus griseus |
| Cell Type | CHO-hD3 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
NGB 2904 and NGB 2849: two highly selective dopamine D3 receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.18 | 8.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL300780 | — | — | 1 | 8.30 |
| CHEMBL54 | HALOPERIDOL | 4.0 | 1 | 8.06 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL300780 | — | IC50 | = | 5.0 | nM | 8.30 |
| CHEMBL54 | HALOPERIDOL | IC50 | = | 8.8 | nM | 8.06 |