Assay Detail

CHEMBL654848

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Functional

Inhibition of collagen-induced blood platelet aggregation in human

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

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Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Cyclic guanidines. 14. Imidazo[1,2-a]thienopyrimidin-2-one derivatives as blood platelet aggregation inhibitors.

Ishikawa F, Kosasayama A, Yamaguchi H, Watanabe Y, Saegusa J, Shibamura S, Sakuma K, Ashida S, Abiko Y.
J Med Chem (1981) 24 : 376 -382
PubMed 7265124 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
EC50	2	6.23	6.30

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL123512	—	—	2	6.30

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL123512	—	EC50	=	500.0	nM	6.30
CHEMBL123512	—	EC50	=	700.0	nM	6.16