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Assay Detail

CHEMBL654866

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was evaluated for the protection of butyrylcholinesterase against DFT in mice and expressed as Ki.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Cholinesterase (CHEMBL2528)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

N-allyl analogues of phencyclidine: chemical synthesis and pharmacological properties.
Kalir A, Teomy S, Amir A, Fuchs P, Lee SA, Holsztynska EJ, Rocki W, Domino EF.
J Med Chem (1984) 27 : 1267 -1271
PubMed 6481761 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 4.75 5.25

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL23436 1 5.25
CHEMBL279924 ETICYCLIDINE 2.0 1 4.24

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL23436 Ki = 5600.0 nM 5.25
CHEMBL279924 ETICYCLIDINE Ki = 58000.0 nM 4.24