Assay Detail
Binding
CHEMBL654926
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Compound was tested for inhibition of Beta-lactamase from Bacillus licheniformis 749/C
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bacillus licheniformis |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Design, synthesis, and evaluation of 2 beta-alkenyl penam sulfone acids as inhibitors of beta-lactamases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.40 | 6.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL6461 | Ro-481220 | — | 1 | 6.50 |
| CHEMBL404 | TAZOBACTAM | 4.0 | 1 | 6.29 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL6461 | Ro-481220 | IC50 | = | 320.0 | nM | 6.50 |
| CHEMBL404 | TAZOBACTAM | IC50 | = | 510.0 | nM | 6.29 |