Assay Detail
Binding
CHEMBL655132
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Inhibitory activity towards mouse butyrylcholinesterase
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Interaction of cycloSal-pronucleotides with cholinesterases from different origins. A structure-activity relationship.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.31 | 5.63 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL40302 | — | — | 1 | 5.63 |
| CHEMBL329491 | — | — | 1 | 4.98 |
| CHEMBL97501 | — | — | 1 | - |
| CHEMBL2114386 | — | — | 1 | - |
| CHEMBL2111583 | — | — | 1 | - |
| CHEMBL2165109 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL40302 | — | IC50 | = | 2350.0 | nM | 5.63 |
| CHEMBL329491 | — | IC50 | = | 10500.0 | nM | 4.98 |
| CHEMBL97501 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL2114386 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL2111583 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL2165109 | — | IC50 | >= | 5000.0 | nM | - |