Assay Detail
Binding
CHEMBL655426
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Compound was evaluated for binding affinity against carboxypeptidase A (CPA), expressed as inhibitory constant (Ki)
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
The function of S1 subsite pocket of carboxypeptidase A
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 6.97 | 7.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL58957 | — | — | 1 | 7.96 |
| CHEMBL109520 | — | — | 1 | 7.43 |
| CHEMBL109771 | — | — | 1 | 6.98 |
| CHEMBL111288 | — | — | 1 | 6.95 |
| CHEMBL110988 | — | — | 1 | 6.82 |
| CHEMBL109462 | — | — | 1 | 6.80 |
| CHEMBL109934 | — | — | 1 | 5.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL58957 | — | Ki | = | 11.0 | nM | 7.96 |
| CHEMBL109520 | — | Ki | = | 37.0 | nM | 7.43 |
| CHEMBL109771 | — | Ki | = | 105.0 | nM | 6.98 |
| CHEMBL111288 | — | Ki | = | 112.0 | nM | 6.95 |
| CHEMBL110988 | — | Ki | = | 150.0 | nM | 6.82 |
| CHEMBL109462 | — | Ki | = | 160.0 | nM | 6.80 |
| CHEMBL109934 | — | Ki | = | 1500.0 | nM | 5.82 |