Assay Detail
Functional
CHEMBL655685
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Inhibitory activity against C-C chemokine receptor type 2 (antagonist activity)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
CCR2: characterization of the antagonist binding site from a combined receptor modeling/mutagenesis approach.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.30 | 7.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL41275 | — | — | 1 | 7.57 |
| CHEMBL337246 | — | — | 1 | 7.27 |
| CHEMBL134074 | — | — | 1 | 7.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL41275 | — | IC50 | = | 27.0 | nM | 7.57 |
| CHEMBL337246 | — | IC50 | = | 54.0 | nM | 7.27 |
| CHEMBL134074 | — | IC50 | = | 89.0 | nM | 7.05 |