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Assay Detail

CHEMBL655697

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Binding
Binding affinity for C-C chemokine receptor type 2B was determined
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

C-C chemokine receptor type 2 (CHEMBL4015)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Conformationally restricted indolopiperidine derivatives as potent CCR2B receptor antagonists.
Witherington J, Bordas V, Cooper DG, Forbes IT, Gribble AD, Ife RJ, Berkhout T, Gohil J, Groot PH.
Bioorg Med Chem Lett (2001) 11 : 2177 -2180
PubMed 11514164 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.40 7.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL71707 1 7.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL71707 Ki = 40.0 nM 7.40