Assay Detail
Binding
CHEMBL655757
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Compound was evaluated for the inhibition of Cdc25A phosphatase by using p-nitrophenylphosphate as substrate
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Novel CDC25A phosphatase inhibitors from pyrolysis of 3-alpha-azido-B-homo-6-oxa-4-cholesten-7-one on silica gel.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.22 | 5.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL143584 | — | — | 1 | 5.40 |
| CHEMBL1765353 | DYSIDIOLIDE | — | 1 | 5.03 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL143584 | — | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL1765353 | DYSIDIOLIDE | IC50 | = | 9400.0 | nM | 5.03 |