Assay Detail
Binding
CHEMBL655780
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Inhibitory concentration against CD45 protein-tyrosine phosphatase pNPP
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Receptor-type tyrosine-protein phosphatase C (CHEMBL3243) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Potent reversible inhibitors of the protein tyrosine phosphatase CD45.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.04 | 6.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL50878 | — | — | 1 | 6.22 |
| CHEMBL50627 | — | — | 1 | 5.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL50878 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL50627 | — | IC50 | = | 1400.0 | nM | 5.85 |