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Assay Detail

CHEMBL655814

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 1000-3000
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Low affinity immunoglobulin epsilon Fc receptor (CHEMBL2940)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Selective inhibition of low affinity IgE receptor (CD23) processing.
Bailey S, Bolognese B, Buckle DR, Faller A, Jackson S, Louis-Flamberg P, McCord M, Mayer RJ, Marshall LA, Smith DG.
Bioorg Med Chem Lett (1998) 8 : 29 -34
PubMed 9871623 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.00 6.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL440712 1 6.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL440712 IC50 = 1000.0 nM 6.00