Assay Detail
Binding
CHEMBL655882
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Inhibitory concentration against CD4-gp120 binding in the absence of fetal bovine serum (FBS); Range is 0.13-0.5 uM
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Condensed aromatic peptide family of microbial metabolites, inhibitors of CD28-CD80 interactions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.89 | 6.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL506605 | ISOCOMPLESTATIN | — | 1 | 6.89 |
| CHEMBL525803 | CHLOROPEPTIN | — | 1 | 6.89 |
| CHEMBL3143464 | — | — | 1 | 6.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL506605 | ISOCOMPLESTATIN | IC50 | = | 130.0 | nM | 6.89 |
| CHEMBL525803 | CHLOROPEPTIN | IC50 | = | 130.0 | nM | 6.89 |
| CHEMBL3143464 | — | IC50 | = | 130.0 | nM | 6.89 |