Assay Detail
Binding
CHEMBL655898
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-Log (Ki) value for butyrylcholinesterase by inhibiting DFP
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
N-allyl analogues of phencyclidine: chemical synthesis and pharmacological properties.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 5.37 | 6.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL23626 | — | — | 1 | 6.30 |
| CHEMBL275528 | PHENCYCLIDINE | 2.0 | 1 | 6.28 |
| CHEMBL23627 | — | — | 1 | 5.59 |
| CHEMBL23436 | — | — | 1 | 5.26 |
| CHEMBL281855 | — | — | 1 | 4.57 |
| CHEMBL279924 | ETICYCLIDINE | 2.0 | 1 | 4.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL23626 | — | Ki | = | 501.19 | nM | 6.30 |
| CHEMBL275528 | PHENCYCLIDINE | Ki | = | 524.81 | nM | 6.28 |
| CHEMBL23627 | — | Ki | = | 2570.4 | nM | 5.59 |
| CHEMBL23436 | — | Ki | = | 5495.41 | nM | 5.26 |
| CHEMBL281855 | — | Ki | = | 26915.35 | nM | 4.57 |
| CHEMBL279924 | ETICYCLIDINE | Ki | = | 57543.99 | nM | 4.24 |