Assay Detail
Functional
CHEMBL655958
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Cytotoxicity of compound against normal human ovarian C18013S cell line
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | C180-13S |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Antiproliferative and phenotype-transforming antitumor agents derived from cysteine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.36 | 7.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL99 | TRICHOSTATIN | 1.0 | 1 | 7.22 |
| CHEMBL101006 | — | — | 1 | 6.40 |
| CHEMBL103508 | — | — | 1 | 6.22 |
| CHEMBL318384 | — | — | 1 | 6.16 |
| CHEMBL103379 | — | — | 1 | 5.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL99 | TRICHOSTATIN | IC50 | = | 60.0 | nM | 7.22 |
| CHEMBL101006 | — | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL103508 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL318384 | — | IC50 | = | 700.0 | nM | 6.16 |
| CHEMBL103379 | — | IC50 | = | 1500.0 | nM | 5.82 |