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Assay Detail

CHEMBL656185

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Growth inhibitory activity against candida albicans.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Candida albicans
Confidence 1 — Organism
Curated By Intermediate

Target

Candida albicans (CHEMBL366)
Type ORGANISM
Organism Candida albicans

Publication

Design and synthesis of novel imidazole-substituted dipeptide amides as potent and selective inhibitors of Candida albicans myristoylCoA:protein N-myristoyltransferase and identification of related tripeptide inhibitors with mechanism-based antifungal activity.
Devadas B, Freeman SK, Zupec ME, Lu HF, Nagarajan SR, Kishore NS, Lodge JK, Kuneman DW, McWherter CA, Vinjamoori DV, Getman DP, Gordon JI, Sikorski JA.
J Med Chem (1997) 40 : 2609 -2625
PubMed 9258368 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 4.29 4.29

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL313161 1 4.29

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL313161 EC50 = 51000.0 nM 4.29