Assay Detail
Functional
CHEMBL656187
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tested to obtain the effective concentration to inhibit candida albicans.
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Candida albicans |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design and synthesis of novel imidazole-substituted dipeptide amides as potent and selective inhibitors of Candida albicans myristoylCoA:protein N-myristoyltransferase and identification of related tripeptide inhibitors with mechanism-based antifungal activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 4.48 | 4.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL86856 | — | — | 1 | 4.48 |
| CHEMBL86687 | — | — | 1 | - |
| CHEMBL89727 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL86856 | — | EC50 | = | 33000.0 | nM | 4.48 |
| CHEMBL86687 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL89727 | — | EC50 | > | 100000.0 | nM | - |