Assay Detail
Functional
CHEMBL656321
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Compound tested for cytotoxic Activity against Capan-l cell line from pancreatic carcinoma
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CAPAN-1 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
On the mechanism of activation of designed enediynes with selective cytotoxicity
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.53 | 7.11 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL15924 | — | — | 1 | 7.11 |
| CHEMBL15828 | — | — | 1 | 5.51 |
| CHEMBL15907 | — | — | 1 | 5.20 |
| CHEMBL277573 | — | — | 1 | 4.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL15924 | — | IC50 | = | 78.0 | nM | 7.11 |
| CHEMBL15828 | — | IC50 | = | 3100.0 | nM | 5.51 |
| CHEMBL15907 | — | IC50 | = | 6300.0 | nM | 5.20 |
| CHEMBL277573 | — | IC50 | = | 50000.0 | nM | 4.30 |