Assay Detail
Functional
CHEMBL656373
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Transcriptional activation in COS cells expressing PPAR gamma and RXR alpha; values in the parentheses indicates 95% confidence interval
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Cell Type | COS |
| Confidence | 6 — Multiple protein complex / RNA |
| Curated By | Expert |
Publication
Novel 5-substituted 2,4-thiazolidinedione and 2,4-oxazolidinedione derivatives as insulin sensitizers with antidiabetic activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 6.31 | 6.31 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1715 | PIOGLITAZONE HYDROCHLORIDE | 4.0 | 1 | 6.31 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1715 | PIOGLITAZONE HYDROCHLORIDE | EC50 | = | 490.0 | nM | 6.31 |