Assay Detail
Binding
CHEMBL656535
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The compound was evaluated for its inhibitory activity towards Protein tyrosine phosphatase of CD45
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Receptor-type tyrosine-protein phosphatase C (CHEMBL3243) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Synthesis and characterization of a potent and selective protein tyrosine phosphatase inhibitor, 2.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.04 | 6.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL89067 | — | — | 1 | 6.55 |
| CHEMBL86473 | VANADATE | — | 1 | 4.47 |
| CHEMBL87002 | — | — | 1 | 4.09 |
| CHEMBL89824 | — | — | 1 | - |
| CHEMBL314528 | — | — | 1 | - |
| CHEMBL90953 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL89067 | — | IC50 | = | 280.0 | nM | 6.55 |
| CHEMBL86473 | VANADATE | IC50 | = | 34200.0 | nM | 4.47 |
| CHEMBL87002 | — | IC50 | = | 80500.0 | nM | 4.09 |
| CHEMBL89824 | — | IC50 | = | 380000.0 | nM | - |
| CHEMBL314528 | — | IC50 | > | 1000000.0 | nM | - |
| CHEMBL90953 | — | IC50 | = | 120000.0 | nM | - |