Assay Detail
Binding
CHEMBL656548
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [125I]IL-8 from CHO cell membranes expressing human CX3C chemokine receptor 2
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | CHO |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Nicotinanilides as inhibitors of neutrophil chemotaxis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.49 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL38182 | — | — | 1 | 8.00 |
| CHEMBL431511 | — | — | 1 | 7.50 |
| CHEMBL39740 | — | — | 1 | 6.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL38182 | — | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL431511 | — | IC50 | = | 32.0 | nM | 7.50 |
| CHEMBL39740 | — | IC50 | = | 110.0 | nM | 6.96 |