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Assay Detail

CHEMBL656587

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound was evaluated for growth inhibition against CH1cisR wild-type ovarian cell lines
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type CH1cisR
Confidence 1 — Organism
Curated By Intermediate

Target

CH1 (CHEMBL614455)
Type CELL-LINE
Organism Homo sapiens

Publication

Synthesis and biological evaluation of novel chloroethylaminoanthraquinones with potent cytotoxic activity against cisplatin-resistant tumor cells.
Pors K, Paniwnyk Z, Ruparelia KC, Teesdale-Spittle PH, Hartley JA, Kelland LR, Patterson LH.
J Med Chem (2004) 47 : 1856 -1859
PubMed 15027879 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.55 5.62

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL54868 1 5.62
CHEMBL418094 1 5.48

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL54868 IC50 = 2400.0 nM 5.62
CHEMBL418094 IC50 = 3300.0 nM 5.48