Assay Detail
Functional
CHEMBL656590
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The compound was tested for cytotoxic activity against CH1 cell line(human ovarian carcinoma )
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CH1 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
N4-(omega-Aminoalkyl)-1-[(omega-aminoalkyl)amino]-4- acridinecarboxamides: novel, potent, cytotoxic, and DNA-binding agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.11 | 8.20 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 8.20 |
| CHEMBL342519 | — | — | 1 | 7.05 |
| CHEMBL141654 | — | — | 1 | 6.07 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 6.3 | nM | 8.20 |
| CHEMBL342519 | — | IC50 | = | 89.0 | nM | 7.05 |
| CHEMBL141654 | — | IC50 | = | 860.0 | nM | 6.07 |