Assay Detail
Functional
CHEMBL656740
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Inhibition of p24 antigen formation in infected C8166-cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | C8166 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and anti-HIV-1 activity of a series of imidazo[1,5-b]pyridazines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 8.28 | 8.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL121820 | — | — | 1 | 8.40 |
| CHEMBL125446 | — | — | 1 | 8.30 |
| CHEMBL268871 | L-697661 | — | 1 | 8.15 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL121820 | — | EC50 | = | 4.0 | nM | 8.40 |
| CHEMBL125446 | — | EC50 | = | 5.0 | nM | 8.30 |
| CHEMBL268871 | L-697661 | EC50 | = | 7.0 | nM | 8.15 |