Assay Detail
Binding
CHEMBL656784
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Binding affinity towards human cloned B1 receptor was determined using [3H][des-Arg10-Leu9]-kallidin as radioligand
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
A rational approach to the design and synthesis of a new bradykinin B(1) receptor antagonist.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 9.13 | 10.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3085458 | — | — | 1 | 10.64 |
| CHEMBL3142392 | — | — | 1 | 7.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3085458 | — | Ki | = | 0.023 | nM | 10.64 |
| CHEMBL3142392 | — | Ki | = | 24.1 | nM | 7.62 |