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Assay Detail

CHEMBL656825

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Functional
Compound was evaluated for its inhibitory activity against multidrug resistance associated protein type 1 (MRP) using potentiation assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Studies on quinazolinones as dual inhibitors of Pgp and MRP1 in multidrug resistance.
Wang S, Ryder H, Pretswell I, Depledge P, Milton J, Hancox TC, Dale I, Dangerfield W, Charlton P, Faint R, Dodd R, Hassan S.
Bioorg Med Chem Lett (2002) 12 : 571 -574
PubMed 11844674 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.52 5.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL421980 1 5.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL421980 EC50 = 3010.0 nM 5.52