Assay Detail
Binding
CHEMBL657120
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity towards Cannabinoid receptor 1 was determined using [3H]-CP- cannabinoid as radioligand with rat brain membrane
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Tissue | Brain |
| Subcellular | Membrane |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Arachidonylsulfonyl derivatives as cannabinoid CB1 receptor and fatty acid amide hydrolase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.02 | 8.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL333149 | ISOPROPYL DODECYLFLUOROPHOSPHONATE | — | 1 | 8.60 |
| CHEMBL97038 | DODECANESULFONYL FLUORIDE | — | 1 | 7.75 |
| CHEMBL113262 | METHOXYARACHIDONOYL FLUOROPHOSPHONATE | — | 1 | 7.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL333149 | ISOPROPYL DODECYLFLUOROPHOSPHONATE | IC50 | = | 2.5 | nM | 8.60 |
| CHEMBL97038 | DODECANESULFONYL FLUORIDE | IC50 | = | 18.0 | nM | 7.75 |
| CHEMBL113262 | METHOXYARACHIDONOYL FLUOROPHOSPHONATE | IC50 | = | 20.0 | nM | 7.70 |