Assay Detail
Binding
CHEMBL657376
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Compound was evaluated for its ability to displace [3H]-L-364,718 from Cholecystokinin type A receptor from rat pancreas
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis and biological activity of 1-alkylcarbonylmethyl analogues of YM022
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 6.15 | 6.53 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL151483 | — | — | 1 | 6.53 |
| CHEMBL357502 | — | — | 1 | 6.36 |
| CHEMBL150869 | — | — | 1 | 6.32 |
| CHEMBL356191 | — | — | 1 | 6.14 |
| CHEMBL153308 | — | — | 1 | 5.92 |
| CHEMBL347329 | — | — | 1 | 5.60 |
| CHEMBL356386 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL151483 | — | IC50 | = | 293.0 | nM | 6.53 |
| CHEMBL357502 | — | IC50 | = | 440.0 | nM | 6.36 |
| CHEMBL150869 | — | IC50 | = | 480.0 | nM | 6.32 |
| CHEMBL356191 | — | IC50 | = | 720.0 | nM | 6.14 |
| CHEMBL153308 | — | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL347329 | — | IC50 | = | 2500.0 | nM | 5.60 |
| CHEMBL356386 | — | IC50 | > | 10000.0 | nM | - |