Assay Detail
Binding
CHEMBL657656
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Inhibitory activity against high affinity binding site of Bradykinin receptor in rat uterus membrane was reported.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Tissue | Uterus |
| Subcellular | Membrane |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Highly selective bradykinin agonists and antagonists with replacement of proline residues by N-methyl-D- and L-phenylalanine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 10.48 | 11.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL406291 | BRADYKININ | 2.0 | 1 | 11.00 |
| CHEMBL2371657 | — | — | 1 | 9.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL406291 | BRADYKININ | IC50 | = | 0.01 | nM | 11.00 |
| CHEMBL2371657 | — | IC50 | = | 0.11 | nM | 9.96 |