Assay Detail
Binding
CHEMBL657904
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Binding affinity towards Cannabinoid receptor 1 using CP-55940 as radioligand in HEK293 EBNA cells
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | HEK293-EBNA |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis and testing of novel phenyl substituted side-chain analogues of classical cannabinoids.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 7.69 | 9.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL325389 | — | — | 1 | 9.24 |
| CHEMBL119592 | — | — | 1 | 7.91 |
| CHEMBL118028 | — | — | 1 | 7.76 |
| CHEMBL465 | DRONABINOL | 4.0 | 1 | 7.54 |
| CHEMBL408123 | — | — | 1 | 7.17 |
| CHEMBL116784 | — | — | 1 | 6.53 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL325389 | — | Ki | = | 0.57 | nM | 9.24 |
| CHEMBL119592 | — | Ki | = | 12.3 | nM | 7.91 |
| CHEMBL118028 | — | Ki | = | 17.3 | nM | 7.76 |
| CHEMBL465 | DRONABINOL | Ki | = | 28.5 | nM | 7.54 |
| CHEMBL408123 | — | Ki | = | 67.6 | nM | 7.17 |
| CHEMBL116784 | — | Ki | = | 297.0 | nM | 6.53 |