Assay Detail
Functional
CHEMBL657921
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Inhibitory activity towards Carbonic anhydrase II
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Successful virtual screening for novel inhibitors of human carbonic anhydrase: strategy and experimental confirmation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.47 | 8.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL20 | ACETAZOLAMIDE | 4.0 | 1 | 8.47 |
| CHEMBL120418 | — | — | 1 | 8.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL20 | ACETAZOLAMIDE | IC50 | = | 3.4 | nM | 8.47 |
| CHEMBL120418 | — | IC50 | = | 3.5 | nM | 8.46 |