Assay Detail
Binding
CHEMBL658057
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Compound was evaluated for the inhibition of dansylamide at human carbonic anhydrase II
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Thieno[2,3-b]furan-2-sulfonamides as topical carbonic anhydrase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 8 | 8.23 | 8.91 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL105080 | — | — | 1 | 8.91 |
| CHEMBL103143 | — | — | 1 | 8.59 |
| CHEMBL101370 | — | — | 1 | 8.47 |
| CHEMBL103255 | — | — | 1 | 8.44 |
| CHEMBL105713 | — | — | 1 | 8.13 |
| CHEMBL101371 | — | — | 1 | 8.09 |
| CHEMBL103621 | — | — | 1 | 7.72 |
| CHEMBL103087 | — | — | 1 | 7.49 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL105080 | — | Ki | = | 1.24 | nM | 8.91 |
| CHEMBL103143 | — | Ki | = | 2.6 | nM | 8.59 |
| CHEMBL101370 | — | Ki | = | 3.4 | nM | 8.47 |
| CHEMBL103255 | — | Ki | = | 3.6 | nM | 8.44 |
| CHEMBL105713 | — | Ki | = | 7.4 | nM | 8.13 |
| CHEMBL101371 | — | Ki | = | 8.2 | nM | 8.09 |
| CHEMBL103621 | — | Ki | = | 19.0 | nM | 7.72 |
| CHEMBL103087 | — | Ki | = | 32.3 | nM | 7.49 |