Assay Detail
Functional
CHEMBL658105
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Inhibitory activity against HCMV DNA polymerase in virus infected cells
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human betaherpesvirus 5 |
| Confidence | 3 — Cell-line / Tissue |
| Curated By | Intermediate |
Publication
Haloanilino derivatives of pyrimidines, purines, and purine nucleoside analogs: synthesis and activity against human cytomegalovirus.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 4.27 | 4.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL52034 | — | — | 1 | 4.35 |
| CHEMBL298714 | — | — | 1 | 4.19 |
| CHEMBL51501 | — | — | 1 | - |
| CHEMBL51613 | — | — | 1 | - |
| CHEMBL301283 | — | — | 1 | - |
| CHEMBL53912 | — | — | 1 | - |
| CHEMBL54127 | — | — | 1 | - |
| CHEMBL53307 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL52034 | — | IC50 | = | 45000.0 | nM | 4.35 |
| CHEMBL298714 | — | IC50 | = | 65000.0 | nM | 4.19 |
| CHEMBL51501 | — | IC50 | = | 250000.0 | nM | - |
| CHEMBL51613 | — | IC50 | = | 330000.0 | nM | - |
| CHEMBL301283 | — | IC50 | = | 175000.0 | nM | - |
| CHEMBL53912 | — | IC50 | = | 150000.0 | nM | - |
| CHEMBL54127 | — | IC50 | = | 360000.0 | nM | - |
| CHEMBL53307 | — | IC50 | = | 140000.0 | nM | - |