Assay Detail
Binding
CHEMBL658126
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Inhibition of rat brain Casein kinase II
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and protein kinase C inhibitory activities of acyclic balanol analogs that are highly selective for protein kinase C over protein kinase A.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.01 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL60254 | BALANOL | — | 1 | 7.52 |
| CHEMBL358264 | — | — | 1 | 4.50 |
| CHEMBL148745 | — | — | 1 | - |
| CHEMBL295806 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL60254 | BALANOL | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL358264 | — | IC50 | = | 32000.0 | nM | 4.50 |
| CHEMBL148745 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL295806 | — | IC50 | > | 50000.0 | nM | - |