Assay Detail
Binding
CHEMBL658756
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The compound was tested for the inhibition of [3H]propionyl specific binding to Cholecystokinin 8 receptor of guinea pig brain
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Full agonists of CCK8 containing a nonhydrolyzable sulfated tyrosine residue.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 8.61 | 9.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL428666 | — | — | 1 | 9.64 |
| CHEMBL218455 | — | — | 1 | 8.52 |
| CHEMBL262687 | — | — | 1 | 8.49 |
| CHEMBL217767 | — | — | 1 | 7.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL428666 | — | Ki | = | 0.23 | nM | 9.64 |
| CHEMBL218455 | — | Ki | = | 3.0 | nM | 8.52 |
| CHEMBL262687 | — | Ki | = | 3.2 | nM | 8.49 |
| CHEMBL217767 | — | Ki | = | 16.0 | nM | 7.80 |