Assay Detail
Binding
CHEMBL658781
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of [125I]BH-CCK-9 binding to Cholecystokinin receptor of guinea pig brain membranes
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Synthesis and biological activities of pseudopeptide analogues of the C-terminal heptapeptide of cholecystokinin. On the importance of the peptide bonds.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 7.12 | 9.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1159912 | — | — | 1 | 9.30 |
| CHEMBL1159915 | — | — | 1 | 9.22 |
| CHEMBL1159903 | — | — | 1 | 8.70 |
| CHEMBL1159910 | — | — | 1 | 7.52 |
| CHEMBL1159909 | — | — | 1 | 6.70 |
| CHEMBL1159904 | — | — | 1 | 6.22 |
| CHEMBL1159905 | — | — | 1 | 6.00 |
| CHEMBL1159906 | — | — | 1 | 5.22 |
| CHEMBL1159911 | — | — | 1 | 5.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1159912 | — | IC50 | = | 0.5 | nM | 9.30 |
| CHEMBL1159915 | — | IC50 | = | 0.6 | nM | 9.22 |
| CHEMBL1159903 | — | IC50 | = | 2.0 | nM | 8.70 |
| CHEMBL1159910 | — | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL1159909 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL1159904 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL1159905 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL1159906 | — | IC50 | = | 6000.0 | nM | 5.22 |
| CHEMBL1159911 | — | IC50 | = | 7000.0 | nM | 5.16 |