Assay Detail
Binding
CHEMBL658971
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Compound was tested for its binding affinity against mouse spleen Cannabinoid receptor 2 using [3H]CP-55940 as radioligand
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Tissue | Spleen |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Pharmacophoric requirements for the cannabinoid side chain. Probing the cannabinoid receptor subsite at C1'.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 8.15 | 9.31 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL411626 | — | — | 1 | 9.31 |
| CHEMBL476325 | — | — | 1 | 9.28 |
| CHEMBL108868 | — | — | 1 | 8.72 |
| CHEMBL108392 | — | — | 1 | 8.44 |
| CHEMBL325135 | — | — | 1 | 7.71 |
| CHEMBL111345 | — | — | 1 | 6.99 |
| CHEMBL322112 | — | — | 1 | 6.59 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL411626 | — | Ki | = | 0.49 | nM | 9.31 |
| CHEMBL476325 | — | Ki | = | 0.52 | nM | 9.28 |
| CHEMBL108868 | — | Ki | = | 1.92 | nM | 8.72 |
| CHEMBL108392 | — | Ki | = | 3.6 | nM | 8.44 |
| CHEMBL325135 | — | Ki | = | 19.7 | nM | 7.71 |
| CHEMBL111345 | — | Ki | = | 103.0 | nM | 6.99 |
| CHEMBL322112 | — | Ki | = | 257.0 | nM | 6.59 |