Assay Detail
Binding
CHEMBL659378
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Inhibitory activity against chicken gizzard smooth muscle calpain
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
The synthesis of ketomethylene pseudopeptide analogues of dipeptide aldehyde inhibitors of calpain.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.98 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL423112 | — | — | 1 | 8.00 |
| CHEMBL32059 | — | — | 1 | 5.60 |
| CHEMBL31728 | — | — | 1 | 4.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL423112 | — | Ki | = | 10.0 | nM | 8.00 |
| CHEMBL32059 | — | Ki | = | 2500.0 | nM | 5.60 |
| CHEMBL31728 | — | Ki | = | 45000.0 | nM | 4.35 |