Assay Detail
Functional
CHEMBL659380
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory activity against on calpain in C6 glial cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Cell Type | C6 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Novel dual inhibitors of calpain and lipid peroxidation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.63 | 4.63 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3706732 | — | — | 1 | 4.63 |
| CHEMBL333995 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3706732 | — | IC50 | = | 23490.0 | nM | 4.63 |
| CHEMBL333995 | — | IC50 | > | 100000.0 | nM | - |