Assay Detail
Binding
CHEMBL659699
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The compound was evaluated for its affinity towards cannabinoid receptor 1 (CB1) in rat brain
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Tissue | Brain |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Pharmacophoric requirements for cannabinoid side chains: multiple bond and C1'-substituted delta 8-tetrahydrocannabinols.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 8.16 | 9.49 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL476325 | — | — | 1 | 9.49 |
| CHEMBL279147 | — | — | 1 | 9.19 |
| CHEMBL19847 | — | — | 1 | 8.66 |
| CHEMBL418555 | — | — | 1 | 7.66 |
| CHEMBL19691 | — | — | 1 | 7.06 |
| CHEMBL418366 | — | — | 1 | 6.87 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL476325 | — | Ki | = | 0.32 | nM | 9.49 |
| CHEMBL279147 | — | Ki | = | 0.65 | nM | 9.19 |
| CHEMBL19847 | — | Ki | = | 2.17 | nM | 8.66 |
| CHEMBL418555 | — | Ki | = | 21.7 | nM | 7.66 |
| CHEMBL19691 | — | Ki | = | 86.4 | nM | 7.06 |
| CHEMBL418366 | — | Ki | = | 136.0 | nM | 6.87 |