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Assay Detail

CHEMBL659836

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory activity against Cathepsin B
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Expert

Target

Cathepsin B (CHEMBL4072)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Potent and selective inhibitors of the proteasome: dipeptidyl boronic acids.
Adams J, Behnke M, Chen S, Cruickshank AA, Dick LR, Grenier L, Klunder JM, Ma YT, Plamondon L, Stein RL.
Bioorg Med Chem Lett (1998) 8 : 333 -338
PubMed 9871680 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.21 8.21

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL114388 1 8.21

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL114388 Ki = 6.1 nM 8.21