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Assay Detail

CHEMBL659848

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Dissociation constant against Carbonic anhydrase II was reported in experiment 1
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Carbonic anhydrase 2 (CHEMBL205)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Successful virtual screening for novel inhibitors of human carbonic anhydrase: strategy and experimental confirmation.
Grüneberg S, Stubbs MT, Klebe G.
J Med Chem (2002) 45 : 3588 -3602
PubMed 12166932 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 9.43 9.43

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL218490 DORZOLAMIDE 4.0 1 9.43

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL218490 DORZOLAMIDE Ki = 0.372 nM 9.43