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Assay Detail

CHEMBL660024

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
In vitro binding for half maximal inhibition of [125I]- Bolton-Hunter-CCK-8 in guinea pig pancreas
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Cavia porcellus
Confidence 9 — Direct single protein target
Curated By Intermediate

Target

Cholecystokinin receptor type A (CHEMBL3501)
Type SINGLE PROTEIN
Organism Cavia porcellus

Publication

CCK-A-selective tetrapeptides containing lys(N epsilon)-amide residues: favorable in vivo and in vitro effects of N-methylation at the aspartyl residue.
Bennett MJ, Nikkel AL, Bianchi BR, Miller TR, Bednarz L, Witte DG, Stashko M, Wang SS, Gore PA, Asin KE.
J Med Chem (1994) 37 : 1569 -1571
PubMed 8201591 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.55 7.55

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL432864 1 7.55

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL432864 IC50 = 28.0 nM 7.55