Assay Detail
Binding
CHEMBL660171
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition concentration by inhibition of carbonic anhydrase from myelin in Rat. 95% confidence limits are given in parentheses.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Structure-activity studies on anticonvulsant sugar sulfamates related to topiramate. Enhanced potency with cyclic sulfate derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.58 | 7.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL417656 | — | — | 1 | 7.28 |
| CHEMBL220492 | TOPIRAMATE | 4.0 | 1 | 5.87 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL417656 | — | IC50 | = | 52.0 | nM | 7.28 |
| CHEMBL220492 | TOPIRAMATE | IC50 | = | 1360.0 | nM | 5.87 |