Assay Detail
Binding
CHEMBL660277
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Compound was tested for its inhibitory activity against cathepsin L
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Peptidyl aldehyde derivatives as potent and selective inhibitors of cathepsin L
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 8.42 | 9.13 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL36801 | — | — | 1 | 9.13 |
| CHEMBL418606 | — | — | 1 | 9.11 |
| CHEMBL36146 | — | — | 1 | 9.07 |
| CHEMBL36904 | — | — | 1 | 8.53 |
| CHEMBL36969 | — | — | 1 | 8.16 |
| CHEMBL430922 | — | — | 1 | 7.81 |
| CHEMBL191881 | LEUPEPTIN | — | 1 | 7.15 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL36801 | — | IC50 | = | 0.74 | nM | 9.13 |
| CHEMBL418606 | — | IC50 | = | 0.78 | nM | 9.11 |
| CHEMBL36146 | — | IC50 | = | 0.85 | nM | 9.07 |
| CHEMBL36904 | — | IC50 | = | 2.95 | nM | 8.53 |
| CHEMBL36969 | — | IC50 | = | 6.96 | nM | 8.16 |
| CHEMBL430922 | — | IC50 | = | 15.5 | nM | 7.81 |
| CHEMBL191881 | LEUPEPTIN | IC50 | = | 70.3 | nM | 7.15 |