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Assay Detail

CHEMBL660461

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
The compound was evaluated for the binding affinity against bovine pancreatic chymotrypsinogen
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Chymotrypsin-C (CHEMBL2386)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Design of orally active, non-peptidic inhibitors of human leukocyte elastase.
Brown FJ, Andisik DW, Bernstein PR, Bryant CB, Ceccarelli C, Damewood JR, Edwards PD, Earley RA, Feeney S, Green RC.
J Med Chem (1994) 37 : 1259 -1261
PubMed 8176703 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.26 7.26

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL11391 1 7.26

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL11391 Ki = 55.0 nM 7.26