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Assay Detail

CHEMBL660571

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Tested against human colon carcinoma COLO 480 cell line in vitro
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type COLO 480
Confidence 1 — Organism
Curated By Intermediate

Target

COLO 480 (CHEMBL614032)
Type CELL-LINE
Organism Homo sapiens

Publication

2-substituted 1,2-dihydro-3H-dibenz[de,h]isoquinoline-1,3-diones. A new class of antitumor agent.
Sami SM, Dorr RT, Alberts DS, Remers WA.
J Med Chem (1993) 36 : 765 -770
PubMed 8459403 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.52 8.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL290677 AZONAFIDE 1 8.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL290677 AZONAFIDE IC50 = 3.0 nM 8.52